To explore the feasibility of using indocyanine green(ICG) visualizing the deep infiltrating endometriosis (DIE) during robotic surgery.

A patient with DIE in Department of Genecology and Obstetrics, Chinese PLA General Hospital was selected and underwent total hysterectomy with bilateral adnexectomy and endometriosis lesion excision with perfect preoperative examination and no surgical contraindication. Near-infrared fluorescence imaging with indocyanine green was used in the operation to visualize the endometriosis lesions.

The location of the lesions were accurate and the patient discharged from hospital successfully.

Near-infrared fluorescence imaging system with indocyanine green may clearly visualize the deep infiltrating endometriosis during robotic surgery. It is characterized by brief operation, accuracy and real time. With this technique, we can comprehensively evaluate the scope of our surgery.

Objective To analyze the disease spectrum and clinical characteristics of 1 316 patients with interstitial lung disease (ILD).

The clinical data of 1316 patients with ILD diagnosed and treated in our hospital from January 2015 to December 2021 were collected, and the disease spectrum and clinical characteristics of ILD in this population were analyzed.

In the disease spectrum of ILD cases, 602 cases (45.74%) were connective tissue disease associated interstitial lung disease (CTD-ILD), including 174 cases (13.22%) of idiopathic inflammatory myopathy associated interstitial lung disease (IIM-ILD). 339 cases (25.76%) were rare diseases. The diagnosis of 60 patients evolved during the follow-up, most of them were IIP patients who gradually developed CTD related symptoms and signs, or IPAF patients diagnosed with CTD-ILD. Among the imaging subtypes of ILD, 604 cases were non-specific interstitial pneumonia (NSIP) and 414 cases were common interstitial pneumonia (UIP); Chest imaging of CTD-ILD patients mainly showed NSIP, organized pneumonia (OP), NSIP+ OP. In terms of comorbidities, 48 cases were complicated with malignant tumors and 132 cases with pulmonary hypertension (PH). Acute exacerbation occurred in 54 cases (4.10%). Other complications include infection, pneumothorax, mediastinal emphysema, etc.

CTD-ILD accounts for a large proportion in ILD population. The diagnosis of ILD often requires dynamic follow-up, and the occurrence of acute exacerbation, lung cancer, pulmonary hypertension, infection, pneumothorax, and mediastinal emphysema should be vigilant.

The most common manifestations of increased intracranial pressure are headache and visual impairment, and obesity is an underrecognized risk factor for intracranial hypertension in children. This article introduces the diagnosis and treatment process of two obese children with intracranial hypertension, aiming to improve clinicians' understanding of the disease and early intervention in childhood obesity to reduce the occurrence of multiple complications and improve the quality of life.

This article reports a case of successful treatment of gastric stenosis after sleeve gastrectomy (SG) using sleeve gastrectomy-transit bipartition (SG-TB). The patient was a 39-year-old female who developed gastric stenosis after sleeve gastrectomy (SG) for obesity in October 2022. She underwent four endoscopic balloon dilations with poor results and received SG-TB in September 2024. After revisional surgery, the patient's symptoms of dysphagia and other gastric stenosis-related issues significantly improved, and her quality of life was markedly enhanced. No complications were observed during the 10-month follow-up.

To explore the effect of mind mapping combined with case-based learning (CBL) method in clinical teaching of nephrology.

A total of 50 residents and graduate students who participated in standardized training in the Department of Internal Medicine of the First Medical Center of the Chinese PLA General Hospital from October 2021 to October 2023 were selected as the study subjects and randomly divided into two groups, a test group (mind mapping+ CBL, n=25) and a control group (traditional teaching method, n=25). The test group was taught with mind mapping combined with CBL employing a "symptoms - examination - diagnosis - treatment" closed-loop training approach, while the control group were taught with the traditional teaching method. The theoretical and practical skill scores as well as teaching satisfaction were compared between the two groups.

The test group achieved significantly higher theoretical scores (92.60±3.27 vs 90.08±2.86, P=0.006) and practical skill scores (89.44±2.77 vs 87.12±4.04, P=0.022) than the control group. The teaching satisfaction survey also showed that the test group had higher ratings for clarity of teaching objectives [8.00 (7.00-8.00] vs. 7.00 (6.00-7.00), P=0.005), practicality of teaching methods [8.00 (8.00-9.00] vs. 7.00 (6.00-8.00], P=0.002), and total satisfaction score (30.48±3.00 vs. 27.84±3.84, P=0.009) than the control group.

Compared with traditional teaching method, the mind mapping combined with CBL in clinical teaching of nephrology effectively enhanced the learners′ learning outcomes in both theoretical knowledge and practical skills of nephrology.

To explore clinical characteristics and treatment results of a child with distal renal tubular acidosis (dRTA) accompanied by peripheral nerve injury and suspected medullary sponge kidney, and review related literature.

One girl (patient 1) with dRTA accompanied by peripheral nerve injury and suspected medullary sponge kidney who visited West China Second University Hospital, Sichuan University in July 2024 was selected as research subject. Her clinical data were retrospectively analyzed, including medical history, clinical manifestations, laboratory tests and genetic test results, treatment and follow-up results. Literature of children with a confirmed diagnosis of dRTA caused by SLC4A1 gene mutations with peripheral nerve damage and suspected medullary sponge kidney were retrieved with " renal tubular acidosis" " medullary sponge kidney" " peripheral nerve damage" and " SLC4A1" etc. as keywords in CNKI, Wanfang service platform and PubMed database. The procedure followed in this study was in accordance with the requirements of the revised Helsinki Declaration of the World Medical Association. The guardian provides informed consent for the diagnosis and treatment of Patient 1.

①Patient 1 is a 7-year-old female who visited the case collection hospital due to " weakness in both lower limbs for 3 days". The main clinical manifestation of the patient is weakness in both lower limbs, without cough, sore throat, vomiting, diarrhea, lower back pain, limb pain or sensory abnormalities. The results of relevant auxiliary examinations at admission suggest hypokalemia, normal anion gap hyperchlorination metabolic acidosis, elevated muscle enzymes, neurogenic lesions, and suspected medullary sponge kidney. Genetic analysis showed that the patient had a heterozygous mutation of SLC4A1 c. 1765C>T (p.Arg589Cys). Based on her clinical manifestations, auxiliary examinations, and genetic testing results, she was diagnosed as renal tubular acidosis with peripheral nerve damage and suspected medullary sponge kidney. After one month of treatment with oral potassium citrate, B vitamins, and rat nerve growth factor, the patient′s symptoms significantly improved. Reexamination showed that blood gas analysis, electrolyte and muscle enzyme levels have completely returned to normal.②Literature review results: According to the literature search strategy set in this study, no relevant literature reports on children with renal tubular acidosis accompanied by peripheral nerve injury and suspected medullary sponge kidney were found both domestically and internationally.

There are currently no reports of SLC4A1 gene mutations leading to dRTA combined with peripheral nerve damage and medullary sponge kidney. This case proposes the possibility of peripheral nerve damage and medullary sponge kidney being associated with SCL4A1 mutations, which may be a key area for future research. Early completion of WES is of great significance for the early diagnosis of dRTA. Early diagnosis and treatment of children with this disease can improve their prognosis and quality of life.